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Enantioselective addition of phenylacetylene to N ‐aryl arylimines catalyzed by Cu(II)‐pyridine containing N ‐tosylatedaminoimine ligand complex
Author(s) -
Liu Bao,
Zhong Yao,
Li Xingshu
Publication year - 2009
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20649
Subject(s) - phenylacetylene , chemistry , enantioselective synthesis , pyridine , aryl , chirality (physics) , catalysis , ligand (biochemistry) , medicinal chemistry , stereochemistry , organic chemistry , receptor , biochemistry , alkyl , chiral symmetry breaking , physics , quantum mechanics , nambu–jona lasinio model , quark
Chiral tridentate N ‐tosylated pyridine‐containing ligands were prepared and used in the Cu(II)‐catalyzed enantioselective addition of phenylacetylene to N ‐aryl arylimines. Moderate to high enantioselectivities (up to 95% ee) were obtained in very mild reaction conditions. Chirality, 2008. © 2009 Wiley‐Liss, Inc.