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Synthesis of new chiral cis ‐3‐hydroxyazetidines and their application in diethylzinc addition to aldehydes
Author(s) -
Zhang Zhanbin,
Li Min,
Zi Guofu
Publication year - 2007
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20470
Subject(s) - diethylzinc , chemistry , enantiomer , chirality (physics) , enantioselective synthesis , catalysis , enantiomeric excess , organic chemistry , stereochemistry , combinatorial chemistry , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
Abstract A new series of chiral cis ‐3‐hydroxyazetidines have been prepared from ( R )‐1‐phenylethylamine. They have excellent catalytic activities and enantiomeric selectivities in asymmetric addition of diethylzinc to aromatic aldehydes. Chirality, 2007. © 2007 Wiley‐Liss, Inc.