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Parallel kinetic resolution of an oxazolidinone using a quasi ‐enantiomeric combination of [D, 13 C]‐isotopomers of pentafluorophenyl 2‐phenyl propionate
Author(s) -
Coumbarides Gregory S.,
Dingjan Marco,
Eames Jason,
Flinn Anthony,
Northen Julian
Publication year - 2007
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20367
Subject(s) - chemistry , isotopomers , enantiomer , kinetic resolution , chirality (physics) , propionate , stereochemistry , resolution (logic) , kinetic energy , enantiomeric excess , propionates , enantioselective synthesis , organic chemistry , catalysis , molecule , nambu–jona lasinio model , chiral symmetry breaking , physics , quantum mechanics , artificial intelligence , quark , computer science
Parallel kinetic resolution of Evans' phenylglycine derived oxazolidinone using an equimolar combination of quasi ‐enantiomeric active esters (derived from [D, 13 C]‐labeled 2‐phenylpropionic acid) was achieved. The levels of stereocontrol were high, leading to products with predictable configurations. Chirality, 2007. © 2007 Wiley‐Liss, Inc.