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Mutual kinetic separation of isotopomers of pentafluorophenyl 2‐phenyl propionate using quasi‐enantiomeric oxazolidinones
Author(s) -
Chavda Sameer,
Coumbarides Gregory S.,
Dingjan Marco,
Eames Jason,
Flinn Anthony,
Northen Julian
Publication year - 2007
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20364
Subject(s) - chemistry , isotopomers , enantiomer , chirality (physics) , propionate , enantiomeric excess , stereochemistry , combinatorial chemistry , computational chemistry , organic chemistry , enantioselective synthesis , catalysis , molecule , chiral symmetry breaking , physics , quantum mechanics , nambu–jona lasinio model , quark
Mutual separation of an equimolar mixture of quasi‐enantiomeric [D, 13 C]‐labeled isotopomers of pentafluorophenyl 2‐phenylpropionate can be achieved efficiently by use of two quasi‐enantiomeric Evans' oxazolidinones. The levels of stereocontrol were high, leading to products with predictable configurations. Chirality, 2007. © 2007 Wiley‐Liss, Inc.