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Enantioselective phenylacetylene addition to aldehydes and ketones catalyzed by recyclable polymeric Zn(salen) complex
Author(s) -
Pathak Kavita,
Bhatt Achyut P.,
Abdi Sayed H. R.,
Kureshy Rukhsana I.,
Khan NoorUl H.,
Ahmad Irshad,
Jasra Raksh V.
Publication year - 2006
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20337
Subject(s) - phenylacetylene , chemistry , enantioselective synthesis , chirality (physics) , catalysis , organic chemistry , nambu–jona lasinio model , quark , chiral symmetry breaking , physics , quantum mechanics
New polymeric Zn(salen) complex was employed in the enantioselective phenylacetylene addition to aldehydes and ketones to produce corresponding chiral secondary propargylic alcohols with yields (up to 96%) and enantioselectivity (up to 72%) and tertiary propargylic alcohols with yields (up to 79%) and enantioselectivity (up to 68%) at room temperature, with added advantage of four times reuse with retention of enantioselectivity. Chirality, 2006. © 2006 Wiley‐Liss, Inc.