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Asymmetric aza‐Henry reaction of N ‐tosyl imine
Author(s) -
Gao Feifeng,
Zhu Jiang,
Tang Yong,
Deng Minzhi,
Qian Changtao
Publication year - 2006
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20315
Subject(s) - chemistry , tosyl , imine , nitroaldol reaction , organic chemistry , medicinal chemistry , combinatorial chemistry , enantioselective synthesis , catalysis
An efficient stereoselective aza‐Henry reaction of N ‐tosyl imine, catalyzed by the coordination of diethylzinc with a chiral semi‐aza‐crown ligand, with moderate to high ee (up to 83%) is reported. Chirality, 2006. © 2006 Wiley‐Liss, Inc.