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Is the optical rotation sign/absolute configuration relationship still a problem? Examples taken from unnatural quaternary aminoacids
Author(s) -
Ferron Laurent,
Guillen Frédéric,
Coste Servane,
Coquerel Gérard,
Plaquevent JeanChristophe
Publication year - 2006
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20296
Subject(s) - chemistry , sign (mathematics) , optical rotation , absolute configuration , quaternary , chirality (physics) , rotation (mathematics) , analogy , protein quaternary structure , resolution (logic) , stereochemistry , crystallography , geometry , organic chemistry , chiral symmetry , physics , quantum mechanics , linguistics , artificial intelligence , mathematics , protein subunit , philosophy , mathematical analysis , biology , quark , paleontology , biochemistry , nambu–jona lasinio model , gene , computer science
The optical rotation sign/absolute configuration relationships of several α‐methyl‐α‐arylglycines have been reinvestigated by crystallographic methods, as they have been found to be inconsistent in recent literature. Assignments previously made by enzymatic resolution, by analogy with natural tertiary aminoacids were found to be erroneous in the case of these quaternary aminoacids. Chirality, 2006. © 2006 Wiley‐Liss, Inc.