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Circular dichroism studies of carbopeptoid‐cyclodextrins
Author(s) -
Edwards Alison A.,
Fleet George W.J.,
Mayes Ben A.,
Hunter Stuart J.,
Tranter George E.
Publication year - 2005
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20117
Subject(s) - chemistry , circular dichroism , chirality (physics) , crystallography , peptide , stereochemistry , biochemistry , chiral symmetry , physics , quantum mechanics , nambu–jona lasinio model , quark
Abstract A series of sugar amino acids, based on open chain sugars, have been oligomerised and cyclised. The resulting cyclic carbopeptoids have been examined for desirable properties such as host–guest chemistry (as in cyclodextrins) or self‐assembling properties (e.g., peptide nanotubes). Initial studies of these systems, by circular dichroism and X‐ray crystallography, have given valuable insight into their stability and properties. One of the four cyclic species studied was found to interact with ion/molecular probes. Chirality 17:S114–S119, 2005. © 2005 Wiley‐Liss, Inc.