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Reversed‐phase liquid chromatographic enantioseparation by cycloalkylcarboxylates of cellulose and amylose
Author(s) -
Kubota Takateru,
Yamamoto Chiyo,
Okamoto Yoshio
Publication year - 2004
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20040
Subject(s) - chemistry , amylose , cellulose , chromatography , phase (matter) , organic chemistry , starch
Three novel cycloalkylcarboxylates, cyclopentyl, cyclohexyl, and 1‐adamantylcarboxylates of cellulose and amylose were prepared and their chiral recognition abilities as chiral stationary phases (CSPs) for high‐performance liquid chromatography (HPLC) were evaluated using a methanol–water mobile phase. Among these esters, cellulose tris(cyclohexylcarboxylate) showed a relatively high chiral recognition ability. The 1‐adamantylcarboxylates of cellulose and amylose showed dissimilar chiral recognition abilities from the other two, probably due to the low degree of substitution and the high hydrophobicity of this group. Chirality 16:309–313, 2004. © 2004 Wiley‐Liss, Inc.