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One‐pot multi‐substrate screening in asymmetric catalysis
Author(s) -
Gao Xiang,
Kagan Henri B.
Publication year - 1998
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.19
Subject(s) - chemistry , borane , catalysis , chirality (physics) , substrate (aquarium) , enantioselective synthesis , reduction (mathematics) , combinatorial chemistry , organic chemistry , chiral symmetry , physics , oceanography , geometry , mathematics , quantum mechanics , geology , nambu–jona lasinio model , quark
Abstract The advantages and disadvantages of the one‐pot multi‐substrate screening in asymmetric catalysis are discussed. The specific case of asymmetric reduction of ketones has been studied and is examplified by borane reduction catalyzed by an oxazaborolidine derived from ( S )‐diphenylproline. Chirality 10:120–124, 1998. © 1998 Wiley‐Liss,Inc.