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Some applications of a chiral fluorometric reagent, ( S )‐TBMB carboxylic acid
Author(s) -
Meguro Hiroshi,
Kim JeongHwan,
Bai Chen,
Nishida Yoshihiro,
Ohrui Hiroshi
Publication year - 2001
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.1059
Subject(s) - chemistry , chirality (physics) , enantiomer , chromophore , reagent , carboxylic acid , chiral derivatizing agent , organic chemistry , glycosyl , combinatorial chemistry , stereochemistry , chiral column chromatography , chiral symmetry breaking , physics , quantum mechanics , nambu–jona lasinio model , quark
Abstract Molecular design and applications of a fluorometric chiral agent, ( S )‐TBMB carboxylic acid, are briefly reviewed. The agent, possessing an asymmetric 1,3‐benzodioxole skeleton, was designed as a novel class of chiral agent that functions also as a benzoate chromophore for exciton chirality CD methods. The utility of this agent has been demonstrated in an application to determine enantiomeric amino acids, acyl‐sn‐glycerols, glycosyl‐sn‐glycerols, and other chiral alcohols and amines. Chirality 13:441–445, 2001. © 2001 Wiley‐Liss, Inc.