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Molecular design of DABNTf as a highly efficient resolving reagent for racemic Pd complex with Tropos biphenylphosphine (BIPHEP) ligand: Circular dichroism (CD) spectra of enantiopure BIPHEP‐Pd complex
Author(s) -
Mikami Koichi,
Yusa Yukinori,
Aikawa Kohsuke,
Hatano Manabu
Publication year - 2002
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.10162
Subject(s) - enantiopure drug , chemistry , ligand (biochemistry) , enantiomer , stereochemistry , palladium , amide , organic chemistry , enantioselective synthesis , catalysis , biochemistry , receptor
The racemic Pd complexes with chirally flexible ( tropos ) biphenylphosphine (BIPHEP) ligands can be resolved but transformed into the enantio‐ and diastereo‐pure complex. The enantiopure metal complex of BIPHEP ligand is thus obtained through enantiomer‐selective complexation of a racemic BIPHEP‐Pd complex with enantiopure 1,1′‐binaphthyl‐2,2′‐di(triflyl)amide, DABNTf. The differential CD spectra of the enantiopure BIPHEP‐Pd complex is also reported. Chirality 15:105–107, 2003. © 2002 Wiley‐Liss, Inc.