Premium
Axially dissymmetric ( R )‐(+)‐5,5′,6,6′,7,7′,8,8′ octahydro‐[1,1′]binaphthyldiimine chiral salen type‐ligands for copper‐catalyzed asymmetric aziridination
Author(s) -
Shi Min,
Wang ChunJiang
Publication year - 2002
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.10107
Subject(s) - chemistry , enantioselective synthesis , ligand (biochemistry) , diimine , cinnamates , catalysis , axial symmetry , chiral ligand , axial chirality , copper , diamine , stereochemistry , medicinal chemistry , combinatorial chemistry , polymer chemistry , organic chemistry , receptor , biochemistry , structural engineering , engineering
Axially dissymmetric chiral diimine ligand 2 was prepared from the reaction of ( R )‐(+)‐5,5′,6,6′,7,7′,8,8′‐octahydro‐[1,1′]binaphthyl‐2,2′‐diamine 1 with 2,6‐dichlorobenzaldehyde. The catalytic asymmetric aziridination of alkenes was examined using this novel chiral ligand. Excellent enantioselective aziridination of cinnamates was achieved using C 2 ‐symmetric chiral ligand 2. Chirality 14:412–416, 2002. © 2002 Wiley‐Liss, Inc.