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Frontispiece: Isopropenyl Esters (iPEs) in Green Organic Synthesis
Author(s) -
Rigo Davide,
Masters Anthony F.,
Maschmeyer Thomas,
Selva Maurizio,
Fiorani Giulia
Publication year - 2022
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202284061
Subject(s) - electrophile , moiety , reactivity (psychology) , transesterification , acetone , chemistry , organic chemistry , catalysis , organic synthesis , coupling reaction , electrophilic addition , polymer chemistry , medicine , alternative medicine , pathology
Isopropenyl esters (iPEs) and isopropenyl acetate (iPAc) are characterised by a tuneable reactivity in organic synthesis. Thanks to the irreversible formation of acetone in transesterification conditions, iPEs are eco‐friendly acylating agents and can be employed for direct biomass modification and/or tandem esterification‐acetalization reactions. C−C and C−X bond formation reactions occur selectively on the isopropenyl moiety via electrophilic and/or radical additions and/or metal‐ and/or photo‐catalyzed cross‐coupling reactions.