Premium
Cover Feature: Brønsted Acid versus Phase‐Transfer Catalysis in the Enantioselective Transannular Aminohalogenation of Enesultams (Chem. Eur. J. 62/2022)
Author(s) -
LuisBarrera Javier,
Rodriguez Sandra,
Uria Uxue,
Reyes Efraim,
Prieto Liher,
Carrillo Luisa,
Pedrón Manuel,
Tejero Tomás,
Merino Pedro,
Vicario Jose L.
Publication year - 2022
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202203257
Subject(s) - enantioselective synthesis , catalysis , merge (version control) , enantiomer , chemistry , phosphoric acid , brønsted–lowry acid–base theory , bromine , stereochemistry , medicinal chemistry , organic chemistry , computer science , information retrieval
Alice points out the preference of one conformational enantiomer by “crossing the mirror” thanks to the catalyst formed from the phosphoric acid and bromine “delivered” by N ‐bromosuccinimide (NBS). Both the selected conformer and the new catalyst formed in situ merge their respective roads to converge on the product. More information can be found in the Research Article by U. Uria, P. Merino, J. L. Vicario, and co‐workers (DOI: 10.1002/chem.202202267).