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Cover Feature: Study of Carbamoyl Fluoride: Synthesis, Properties and Applications (Chem. Eur. J. 43/2022)
Author(s) -
Bonnefoy Clémence,
Chefdeville Emmanuel,
Tourvieille Christian,
Panossian Armen,
Hanquet Gilles,
Leroux Frédéric,
Toulgoat Fabien,
Billard Thierry
Publication year - 2022
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202202043
Subject(s) - fluorine , cover (algebra) , fluoride , combinatorial chemistry , chemistry , molecule , computational chemistry , organic chemistry , inorganic chemistry , engineering , mechanical engineering
Carbamoyl fluorides are among the emerging fluorinated motifs. but are still quite underexplored. So, an efficient, fast, inexpensive, metal‐free and easy‐to‐perform method to access such compounds easily, even with sophisticated molecules, is described. The physicochemical properties of these compounds were measured to give an insight into the potential of carbamoyl fluorides—in particular, their stability under close‐to‐physiological conditions. Finally, a first application in radiochemistry to obtain fluorine‐18 radiolabeled compounds easily is proposed. More information can be found in the Research Article by F. Toulgoat, T. Billard, and co‐workers (DOI: 10.1002/chem.202201589).