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Cover Feature: BOPHY‐Fullerene C 60 Dyad as a Photosensitizer for Antimicrobial Photodynamic Therapy (Chem. Eur. J. 5/2022)
Author(s) -
Gonzalez Lopez Edwin J.,
Sarotti Ariel M.,
Martínez Sol R.,
Macor Lorena P.,
Durantini Javier E.,
Renfige Melisa,
Gervaldo Miguel A.,
Otero Luis A.,
Durantini Andrés M.,
Durantini Edgardo N.,
Heredia Daniel A.
Publication year - 2022
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202200011
Subject(s) - photodynamic therapy , photosensitizer , fullerene , photochemistry , porphyrin , chemistry , acceptor , irradiation , physics , organic chemistry , nuclear physics , condensed matter physics
A heavy‐atom‐free BOPHY‐based photosensitizer (PS) has been obtained as a mixture of two atropisomers. The BOPHY core works as a visible light‐harvesting center and donor antenna, while a fullerene C 60 acceptor acts as an effective spin converter and triggers photodynamic action. The dyad is capable of producing reactive oxygen species (ROS) by both photodynamic mechanisms. In‐vitro studies indicate that the dyad photokills microorganisms after visible light irradiation. More information can be found in the Research Article by D. A. Heredia et al. (DOI: 10.1002/chem.202103884).