Premium
Frontispiece: Fluorine‐18 Radiolabelling and Photophysical Characteristics of Multimodal PET–Fluorescence Molecular Probes
Author(s) -
Klenner Mitchell A.,
Pascali Giancarlo,
Massi Massimiliano,
Fraser Benjamin H.
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202180362
Subject(s) - cyanine , fluorescence , positron emission tomography , molecular imaging , fluorescence lifetime imaging microscopy , chemistry , pet imaging , bodipy , nanotechnology , nuclear medicine , materials science , medicine , optics , in vivo , physics , biology , microbiology and biotechnology
PET–fluorescence multimodal probes provide complimentary information for medical diagnoses. Such probes enable specific functional imaging of a disease state from initial diagnostic positron emission tomography (PET) scans, followed by high spatial resolution, real‐time fluorescence imaging during intraoperative excision of the diseased tissue. Some of the most promising candidates for such imaging probes include quantum dots, rhenium(I) complexes, cyanine and BODIPY dyes, as well as other organic fluorophores. For more details see the Minireview by M. A. Klenner, B. H. Fraser et al. on page 861.