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Cover Feature: Ni(II) Precatalysts Enable Thioetherification of (Hetero)Aryl Halides and Tosylates and Tandem C−S/C−N Couplings (Chem. Eur. J. 48/2021)
Author(s) -
Martín M. Trinidad,
Marín Mario,
Maya Celia,
Prieto Auxiliadora,
Nicasio M. Carmen
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102641
Subject(s) - aryl , electrophile , tandem , chemistry , nucleophile , halide , nickel , combinatorial chemistry , chemoselectivity , coupling (piping) , catalysis , medicinal chemistry , polymer chemistry , organic chemistry , materials science , alkyl , metallurgy , composite material
Competent partners : π‐Allyl–nickel precatalysts supported by dialkylterphenyl phosphines efficiently couple a wide range of electrophiles including aryl iodides/bromides/chlorides and, for the first time, aryl and alkenyl tosylates with aromatic and aliphatic thiols. In addition, tandem C−S and C−N coupling of multi‐electrophile/nucleophile combinations is achieved in a completely chemoselective manner leading to highly functionalized products. More information can be found in the Full Paper by A. Prieto, M. C. Nicasio, et al. (DOI: 10.1002/chem.202101906).