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Isomerization of Functionalized Olefins by Using the Dinuclear Catalyst [Pd I ( μ ‐Br)(P t Bu 3 )] 2 : A Mechanistic Study
Author(s) -
Koley Debasis,
De Sriman,
Sivendran Nardana,
Gooßen Lukas J.
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102554
Subject(s) - isomerization , catalysis , chemistry , dissociation (chemistry) , palladium , kinetic energy , photochemistry , medicinal chemistry , activation barrier , organic chemistry , physics , quantum mechanics
In a combined experimental and computational study, the isomerization activity of the dinuclear palladium(I) complex [Pd I ( μ ‐Br)(P t Bu 3 )] 2 towards allyl arenes, esters, amides, ethers, and alcohols has been investigated. The calculated energy profiles for catalyst activation for two alternative dinuclear and mononuclear catalytic cycles, and for catalyst deactivation are in good agreement with the experimental results. Comparison of experimentally observed E / Z ratios at incomplete conversion with calculated kinetic selectivities revealed that a substantial amount of product must form via the dinuclear pathway , in which the isomerization is promoted cooperatively by two palladium centers. The dissociation barrier towards mononuclear Pd species is relatively high, and once the catalyst enters the energetically more favorable mononuclear pathway , only a low barrier has to be overcome towards irreversible deactivation.