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What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?
Author(s) -
Ramanan Rajeev,
Waheed Sodiq O.,
Schofield Christopher J.,
Christov Christo Z.
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102158
Subject(s) - demethylation , demethylase , arginine , chemistry , substrate (aquarium) , catalysis , protonation , electric field , histone , biochemistry , physics , organic chemistry , biology , quantum mechanics , dna , ecology , ion , gene expression , amino acid , dna methylation , gene
Invited for the cover of this issue are Christo Z. Christov and co‐workers at Michigan Technological University and University of Oxford. The image depicts the effects of applying an external electric field on the demethylation of dimethylated arginine substrate by a non‐heme Fe center Histone N‐methyl arginine demethylase. Read the full text of the article at 10.1002/chem.202101174.