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Aromatic Trifluoromethylselenolation via Pd‐catalyzed C−H functionalization
Author(s) -
Grollier Kevin,
Chefdeville Emmanuel,
Jeanneau Erwann,
Billard Thierry
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102121
Subject(s) - surface modification , palladium , catalysis , reagent , combinatorial chemistry , chemistry , molecule , trifluoromethyl , organic chemistry , alkyl
The synthesis of trifluoromethylselenolated aromatic molecules via an auxiliary‐assisted, palladium catalyzed, C−H bonds functionalization with trifluoromethyl tolueneselenosulfonate as reagent is described. The mono‐ or bis‐products can be preferentially formed. Some mechanistic investigations were realized to better understand the reaction. This methodology was also extended to fluoroalkylselenyl groups.