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Cover Feature: First Total Synthesis of Phytoprostanes with Prostaglandin‐Like Configuration, Evidence for Their Formation in Edible Vegetable Oils and Orienting Study of Their Biological Activity (Chem. Eur. J. 37/2021)
Author(s) -
Smrček Jakub,
Hájek Miroslav,
Hodek Ondřej,
Čížek Karel,
Pohl Radek,
Jahn Emanuela,
Galano JeanMarie,
Oger Camille,
Durand Thierry,
Cvačka Josef,
Jahn Ullrich
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202101937
Subject(s) - chemistry , prostaglandin , edible oil , cover (algebra) , food science , biochemistry , engineering , mechanical engineering
Phytoglandins from the reaction flask enable their identification in Nature. Hypothetical plant‐based prostaglandin analogs were obtained by a 15‐step asymmetric total synthesis. They were applied as an analytical standard in a detailed LC‐MS/MS study confirming phytoglandin formation in autoxidized linolenic acid and in various edible vegetable oils in sizeable quantities. More information can be found in the Full Paper by U. Jahn et al. (DOI: 10.1002/chem.202100872).