Divergent Construction of Diverse Scaffolds through Catalyst‐Controlled C−H Activation Cascades of Quinazolinones and Cyclopropenones | Zendy

Shi Yuesen | Zendy; Huang Tianle | Zendy; Wang Ting | Zendy; Chen Jian | Zendy; Liu Xuexin | Zendy; Wu Zhouping | Zendy; Huang Xiaofang | Zendy; Zheng Yao | Zendy; Yang Zhongzhen | Zendy; Wu Yong | Zendy

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Divergent Construction of Diverse Scaffolds through Catalyst‐Controlled C−H Activation Cascades of Quinazolinones and Cyclopropenones

Author(s) -

Shi Yuesen,

Huang Tianle,

Wang Ting,

Chen Jian,

Liu Xuexin,

Wu Zhouping,

Huang Xiaofang,

Zheng Yao,

Yang Zhongzhen,

Wu Yong

Publication year - 2021

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.202101839

Subject(s) - quinazolinone , cascade , catalysis , construct (python library) , combinatorial chemistry , selectivity , chemistry , cascade reaction , scalability , reaction conditions , computer science , organic chemistry , database , chromatography , programming language

A transition‐metal‐catalyzed C−H activation cascade strategy to rapidly construct diverse quinazolinone derivatives in a one‐pot manner is reported. The catalysts play an important role in the different transformations. Additionally, the procedure is scalable, proceeds with high efficiency and good chemo‐/regio‐selectivity, and tolerates a range of functional groups.

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