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Cover Feature: Surprising Homolytic Gas Phase Co−C Bond Dissociation Energies of Organometallic Aryl‐Cobinamides Reveal Notable Non‐Bonded Intramolecular Interactions (Chem. Eur. J. 25/2021)
Author(s) -
Tsybizova Alexandra,
Brenig Christopher,
Kieninger Christoph,
Kräutler Bernhard,
Chen Peter
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202101335
Subject(s) - chemistry , homolysis , intramolecular force , bond cleavage , aryl , nucleophile , bond dissociation energy , dissociation (chemistry) , photochemistry , triple bond , stereochemistry , computational chemistry , catalysis , polymer chemistry , radical , organic chemistry , double bond , alkyl
B 12 ‐derived phenyl‐corrins are antivitamins B 12 that resist the enzymatic cleavage of their Co−C bond. Surprisingly, as shown by ESI‐MS threshold CID, the Co−C sp2 bonds of phenyl‐corrins are weaker than Co−C sp3 bonds of analogous methyl‐corrins, contrasting the known effect of the hybridization on bond strengths. Hence, for the behavior of phenyl‐cobalamins as antivitamins B 12 , stereo‐electronic restrictions of the nucleophilic displacement are more critical than Co−C bond strengths. More information can be found in the Full Paper by B. Kräutler, P. Chen, et al. (DOI: 10.1002/chem.202004589).