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Cover Feature: Altered Membrane Mechanics Provides a Receptor‐Independent Pathway for Serotonin Action (Chem. Eur. J. 27/2021)
Author(s) -
Dey Simli,
Surendran Dayana,
Engberg Oskar,
Gupta Ankur,
Fanibunda Sashaina E.,
Das Anirban,
Maity Barun Kumar,
Dey Arpan,
Visvakarma Vicky,
Kallianpur Mamata,
Scheidt Holger A.,
Walker Gilbert,
Vaidya Vidita A.,
Huster Daniel,
Maiti Sudipta
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202101333
Subject(s) - serotonin , membrane , receptor , 5 ht receptor , chemistry , biophysics , microbiology and biotechnology , biochemistry , biology
Serotonin is an important signaling molecule with a high lipid membrane affinity. Membrane binding of serotonin modulates membrane properties and potentially cellular function as well, providing an activity pathway completely independent of serotonin receptors. The results presented in this study suggest a mode of serotonin–membrane interaction that can potentiate key cellular processes in a receptor‐independent fashion. More information can be found in the Full Paper by D. Huster, S. Maiti, et al. (DOI: 10.1002/chem.202100328).