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Frontispiece: A Sunscreen‐Based Photocage for Carbonyl Groups
Author(s) -
LinerosRosa Mauricio,
Miranda Miguel A.,
LhiaubetVallet Virginie
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202083263
Subject(s) - photoprotection , context (archaeology) , chemistry , carbonyl group , sunscreening agents , photochemistry , toolbox , chromophore , derivative (finance) , combinatorial chemistry , organic chemistry , computer science , stereochemistry , medicine , business , biochemistry , skin cancer , paleontology , photosynthesis , finance , cancer , biology , programming language
New photolabile protecting group (PPG) for the organic chemist toolbox is described herein. The concept of sunscreen‐based photocages is explored for photoprotection and controlled release of carbonyl compounds. In this context, the commercial UVA/UVB filter oxybenzone not only acts as a mere PPG, but also provides, once released, UV photoprotection to the carbonyl derivative. This design points to a possible therapeutic approach to reduce the severe photoadverse effects of drugs containing a carbonyl chromophore. For more information, see the Full Paper of M. A. Miranda, V. Lhiaubet‐Vallet et al. on page 7205 ff.