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Frontispiece: The Structural Basis for Processing of Unnatural Base Pairs by DNA Polymerases
Author(s) -
Marx Andreas,
Betz Karin
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202081661
Subject(s) - base pair , computational biology , dna , base (topology) , dna polymerase , polymerase , basis (linear algebra) , computer science , genetics , biology , chemistry , mathematics , mathematical analysis , geometry
The integration of artificial unnatural base pairs (UBPs) in DNA structures enhances their applicability in molecular biological and biotechnological approaches. The highly efficient and selective processing of these base pairs by DNA polymerases is the key of many applications. Different base‐pair concepts for these UBPs have been developed and different studies investigating these concepts are highlighted in the Review article by A. Marx and K. Betz on page 3446 ff.

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