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Frontispiece: α‐Imino Gold Carbene Intermediates from Readily Accessible Sulfilimines: Intermolecular Access to Structural Diversity
Author(s) -
Tian Xianhai,
Song Lina,
Hashmi A. Stephen K.
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202081561
Subject(s) - carbene , nitrene , reagent , intermolecular force , chemistry , combinatorial chemistry , catalysis , ylide , molecule , organic chemistry
The golden versatility : Sulfilimines are safe, readily available reagents with a generally good stability. Despite some useful applications, this ylide remains underexplored in modern transition metal catalysis. Recently, these ylides were successfully employed as nitrene‐transfer reagents for the synthesis of complex nitrogen‐containing molecules by means of gold catalysis. In their Concept article on page 3197 ff., A. S. K. Hashmi et al. summarize several scalable synthetic routes towards diverse sulfilimines and highlight the recently reported gold‐catalyzed transformations of these ylides with ynamides, a methodology of high interest for example in pharmaceutical chemistry.