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Frontispiece: The Symbiotic Relationship Between Drug Discovery and Organic Chemistry
Author(s) -
Grygorenko Oleksandr O.,
Volochnyuk Dmitriy M.,
Ryabukhin Sergey V.,
Judd Duncan B.
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202080662
Subject(s) - drug discovery , natural product , chemistry , biochemical engineering , combinatorial chemistry , organic chemistry , nanotechnology , engineering , materials science , biochemistry
Drug discovery uses both natural product sources and synthetic organic chemistry to provide suitable starting points for further optimization. Producing such compounds in a time‐, quality‐, and cost‐efficient manner has become one of the most important applied tasks of the chemical sciences. Similarly, drug discovery has had an impact on the direction of synthetic organic chemistry. In their provide An appraisal of the relationship between synthetic chemistry and early drug discovery, along with a discussion on key concepts such as diversity‐, biology‐, and lead‐oriented syntheses is provided in the Review article by O. Grygorenko and D. Judd et al. on page 1196 ff.