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Additive‐free Aqueous Dispersions of Two‐Dimensional Materials with Glial Cell Compatibility and Enzymatic Degradability
Author(s) -
Lobo Kenneth,
Sahoo Priyabrata,
Kurapati Rajendra,
Krishna K. Vijaya,
Patil Vaibhav,
Pandit Abhay,
Matte H. S. S. Ramakrishna
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202005491
Subject(s) - bioelectronics , materials science , molybdenum disulfide , raman spectroscopy , aqueous solution , chemical engineering , nanosheet , nanotechnology , degradation (telecommunications) , boron nitride , chemistry , organic chemistry , composite material , telecommunications , physics , engineering , computer science , optics , biosensor
Water‐dispersible two‐dimensional (2D) materials are desirable for diverse applications. Aqueous dispersions make processing safer and greener and enable evaluation of these materials on biological and environmental fronts. To evaluate the effects of 2D materials with biological systems, obtaining dispersions without additives is critical and has been a challenge. Herein, a method was developed for obtaining additive‐free aqueous dispersions of 2D materials like transition metal dichalcogenides and hexagonal boron nitride (h‐BN). The nanosheet dispersions were investigated through spectroscopic and microscopic methods, along with the role of size on stability. The aqueous media enabled investigations on cytocompatibility and enzymatic degradation of molybdenum disulphide (MoS 2 ) and h‐BN. Cytocompatibility with mixed glial cells was observed up to concentrations of 100 μg mL −1 , suggesting their plausible usage in bioelectronics. Besides, biodegradation using human myeloperoxidase (hMPO) mediated catalysis was investigated through Raman spectroscopy and electron microscopy. The findings suggested that additive‐free 2H‐MoS 2 and h‐BN were degradable by hMPO, with 2H‐phase exhibiting better resistance to degradation than the 1T‐phase, while h‐BN exhibited slower degradation. The findings pave a path for incorporating 2D materials in the burgeoning field of transient bioelectronics.