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Multidentate, V‐Shaped Pyridine Building Blocks as Tectons for Crystal Engineering
Author(s) -
Guagnini Francesca,
Pedrini Alessando,
Dalcanale Enrico,
Massera Chiara
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202004918
Subject(s) - supramolecular chemistry , crystal engineering , pyridine , steric effects , crystallography , crystallization , materials science , crystal structure , crystal (programming language) , crystal structure prediction , denticity , single crystal , chemistry , nanotechnology , stereochemistry , computer science , organic chemistry , programming language
The formation of supramolecular structural units through self‐assembly is a powerful method to design new architectures and materials endowed with specific properties. With the aim of adding a group of versatile tectons to the toolkit of crystal engineers, we have devised and synthesised four new V‐shaped building blocks characterised by an aryl acetylene scaffold comprising three substituted pyridine rings connected by two triple bonds. The judicious choice of different substituents on the pyridine rings provides these tectons with distinctive steric, electrostatic and self‐assembly properties, which influence their crystal structures and their ability to form co‐crystals. Co‐crystals of the tectons with tetraiododifluorobenzene were obtained both via traditional and mechanochemical crystallisation strategies, proving their potential use in crystal engineering. The energetic contributions of the supramolecular interactions at play in the crystal lattice have also been evaluated to better understand their nature and strength and to rationalise their role in designing molecular crystals.