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Color Tuning of Fluorogens for FAST Fluorogen‐Activating Protein
Author(s) -
Myasnyanko Ivan N.,
Gavrikov Alexey S.,
Zaitseva Snizhana O.,
Smirnov Alexander Yu.,
Zaitseva Elvira R.,
Sokolov Anatolii I.,
Malyshevskaya Kseniya K.,
Baleeva Nadezhda S.,
Mishin Alexander S.,
Baranov Mikhail S.
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202004760
Subject(s) - pallet , chemistry , biophysics , nanotechnology , combinatorial chemistry , computer science , materials science , engineering , biology , mechanical engineering
Using benzylidene imidazolone core, we created a panel of color‐shifted fluorogenic ligands for FAST protein without compromise to the binding efficiency and the utility for live‐cell protein labeling. This study highlights the potential of benzylidene imidazolones derivatives for rapid expansion of a pallet of live‐cell fluorogenic labeling tools.