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Cover Feature: Dual Crosslinking Photo‐Switches for Orthogonal Photo‐Control of Hybridization Between Serinol Nucleic Acid and RNA (Chem. Eur. J. 14/2021)
Author(s) -
Yamano Yuuhei,
Murayama Keiji,
Asanuma Hiroyuki
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202004192
Subject(s) - nucleic acid , nucleobase , rna , chemistry , dna , stereochemistry , biochemistry , gene
A dual photo‐switch method produces four different hybridization states of duplexes by irradiation with a specific wavelength of light: 465 nm, 405 nm, 340 nm, and 300 nm. This photo‐regulation system is based on a reversible photo‐crosslinking reaction between two photo‐responsive nucleobases in serinol nucleic acid strands. The use of a different pair of the photo‐responsive nucleobases realizes an orthogonal photo‐control of two duplexes. More information can be found in the Full Paper by Y. Yamano, K. Murayama, and H. Asanuma on page 4599.