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Enantioselective Construction of Si‐Stereogenic Center via Rhodium‐Catalyzed Intermolecular Hydrosilylation of Alkene
Author(s) -
He Tao,
Liu LiChuan,
Ma WenPeng,
Li Bin,
Zhang QingWei,
He Wei
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202003506
Subject(s) - stereocenter , hydrosilylation , alkene , enantioselective synthesis , rhodium , intermolecular force , catalysis , chemistry , stereochemistry , organic chemistry , molecule
Abstract Catalytic, enantioselective synthesis of stereogenic silicon compounds remains a challenge. Herein, we report a rhodium‐catalyzed regio‐ and enantio‐selective intermolecular hydrosilylation of alkene with prochiral dihydrosilane. This new method features a simple catalytic system, mild reaction conditions and a wide functional group tolerance.