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Cover Feature: Pressure Sensitivity of SynGAP/PSD‐95 Condensates as a Model for Postsynaptic Densities and Its Biophysical and Neurological Ramifications (Chem. Eur. J. 48/2020)
Author(s) -
Cinar Hasan,
Oliva Rosario,
Lin YiHsuan,
Chen Xudong,
Zhang Mingjie,
Chan Hue Sun,
Winter Roland
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202003048
Subject(s) - postsynaptic potential , sensitivity (control systems) , cover (algebra) , high pressure , postsynaptic density , feature (linguistics) , neuroscience , chemistry , physics , psychology , medicine , thermodynamics , philosophy , engineering , mechanical engineering , linguistics , receptor , electronic engineering
A binary protein condensate that mimics postsynaptic densities revealed high pressure sensitivity. This may help to gain a better understanding of the biophysical causes of pressure‐related neurological disorders, such as the high‐pressure neurological syndrome experienced by deep‐sea divers. More information can be found in the Full Paper by R. Winter, H. S. Chan et al. on page 11024).