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Engineering a NO‐Regulated Nanofluidic Sensor through the Cyclization Reaction Strategy
Author(s) -
Han Yunfeng,
Sun Zhongyue,
Sun Ziyan,
Chen Xiaoya,
Zhang Yongxue,
Sun Yao,
Li Haibing
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202001089
Subject(s) - nanotechnology , nanosensor , in vivo , grasp , nitric oxide , materials science , sensitivity (control systems) , chemistry , computer science , engineering , biology , electronic engineering , microbiology and biotechnology , organic chemistry , programming language
Nitric oxide (NO) is known to be a secondary in vivo signaling agent, demonstrating various biological functions through regulating ion flux in channels. Considering the crucial role of NO in vivo, herein, a biomimetic NO‐regulated nanofluidic sensor has been fabricated through a cyclization reaction strategy. This nanofluidic sensor exhibited a promising NO selectivity, sensitivity, and non‐interference performance in complex matrices. Thus, such a NO‐driven nanosensor will be meaningful for scientific researchers to grasp the in vivo functions of NO.