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Cover Feature: Electrochemical‐Induced Ring Transformation of Cyclic α‐( ortho ‐Iodophenyl)‐β‐oxoesters (Chem. Eur. J. 15/2020)
Author(s) -
Strehl Julia,
Kahrs Christoph,
Müller Thomas,
Hilt Gerhard,
Christoffers Jens
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202000281
Subject(s) - ring (chemistry) , electrochemistry , cover (algebra) , transformation (genetics) , chemistry , reaction mechanism , combinatorial chemistry , medicinal chemistry , computational chemistry , organic chemistry , electrode , catalysis , mechanical engineering , biochemistry , engineering , gene
Cyclic α‐( ortho ‐iodophenyl)‐β‐oxoesters were converted in a ring‐expanding transformation through electrochemical reduction to furnish benzannulated cycloalkanone carboxylic esters. A broad variety of starting materials could be converted: cyclic oxoesters with different ring sizes, acyclic oxoesters, and cyclic compounds substituted by diverse functional groups. Additionally, the reaction mechanism was investigated by experiments and DFT calculations. More information can be found in the Communication by T. Müller, G. Hilt, J. Christoffers et al. on page 3222.