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Frontispiece: C−F Bond Activation Mediated by Phosphorus Compounds
Author(s) -
Bayne Julia M.,
Stephan Douglas W.
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201984062
Subject(s) - lewis acids and bases , chemistry , reagent , phosphorus , surface modification , catalysis , combinatorial chemistry , nanotechnology , organic chemistry , materials science
C−F bond activation and functionalization has garnered significant attention in the scientific community as a strategy to mitigate toxicity and environmental concerns, as well as provide new pathways to agro‐ and pharmaceutical chemicals and materials. In recent years, several strategies to C−F bond activation have focused on the use of phosphorus‐based reagents. This Minireview by J. M. Bayne and D. W. Stephan, on page 9350 ff., summarizes strategies that exploit P V ‐ and P III ‐based Lewis acids as well as P III Lewis bases in frustrated Lewis pair (FLP) protocols for synthetic methods involving C−F activation.