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Covalent Organic Frameworks (COFs) for Cancer Therapeutics
Author(s) -
Guan Qun,
Zhou LeLe,
Li WenYan,
Li YanAn,
Dong YuBin
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201905150
Subject(s) - nanotechnology , photothermal therapy , cancer therapy , drug delivery , biocompatibility , materials science , covalent bond , cancer , chemistry , medicine , organic chemistry , metallurgy
As newly emerged crystalline porous materials, covalent organic frameworks (COFs) possess fascinating structures and some specific features such as modularity, crystallinity, porosity, stability, versatility, and biocompatibility. Besides adsorption/separation, sensing, catalysis, and energy applications, COFs have recently shown a promise in biomedical applications. This contribution provides an overview of the recent developments of COF‐based medicines in cancer therapeutics, including drug delivery, photodynamic therapy (PDT), photothermal therapy (PTT), and combined therapy. Furthermore, the major challenges and developing trends in this field are also discussed. These recent developments are summarized and discussed to help encourage further contributions in this emerging and promising field.