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Cover Feature: Adduct of NacNacAl with Benzophenone and Its Coupling Chemistry (Chem. Eur. J. 1/2020)
Author(s) -
Dmitrienko Anton,
Britten James F.,
Spasyuk Denis,
Nikonov Georgii I.
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201904775
Subject(s) - benzophenone , adduct , quinoline , chemistry , photochemistry , nitrile , azide , polymer chemistry , medicinal chemistry , organic chemistry
Like the docking of two space‐ships : The adduct of NacNacAl with benzophenone easily couples with unsaturated substrates. The phenyl ring of benzophenone acts like a switch that opens the port, while the aluminum atom and the α‐carbon are the beacons orienting the incoming molecule. Such a communication between the building blocks of the adduct enables selective coupling with high yields of the products. The scope of substrates includes aldimine, quinoline, phenyl nitrile, trimethyl azide, and a saturated cyclic thiourea. More information can be found in the Full Paper by G. I. Nikonov et al. on page 206.