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Front Cover: Construction of Biaryls from Aryl Sulfoxides and Anilines by Means of a Sigmatropic Rearrangement (Chem. Eur. J. 4/2020)
Author(s) -
Yanagi Tomoyuki,
Nogi Keisuke,
Yorimitsu Hideki
Publication year - 2020
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201904613
Subject(s) - sigmatropic reaction , sulfanyl , aryl , chemistry , front cover , combinatorial chemistry , stereochemistry , medicinal chemistry , computational chemistry , cover (algebra) , organic chemistry , mechanical engineering , alkyl , engineering
A route to biaryls without recourse to transition metal catalysts was devised. Aryl sulfoxides underwent dehydrogenative coupling with unprotected anilines under Pummerer‐type conditions to provide the corresponding 2‐amino‐2′‐sulfanyl‐and/or 4‐amino‐4′‐sulfanylbiphenyls. The C−C bond‐forming sigmatropic rearrangement proceeds from dicationic S−N‐tethered species, which is the key step of this biaryl synthesis. More information can be found in the Communication by H. Yorimitsu et al. on page 783.