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Front Cover: Anticancer Potential of Diiron Vinyliminium Complexes (Chem. Eur. J. 65/2019)
Author(s) -
Rocco Dalila,
Batchelor Lucinda K.,
Agonigi Gabriele,
Braccini Simona,
Chiellini Federica,
Schoch Silvia,
Biver Tarita,
Funaioli Tiziana,
Zacchini Stefano,
Biancalana Lorenzo,
Ruggeri Marina,
Pampaloni Guido,
Dyson Paul J.,
Marchetti Fabio
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201904316
Subject(s) - front cover , selectivity , combinatorial chemistry , aqueous medium , cover (algebra) , chemistry , ligand (biochemistry) , stereochemistry , tumor cells , aqueous solution , cancer research , receptor , biochemistry , biology , catalysis , organic chemistry , mechanical engineering , engineering
Diiron complexes with a bridging vinyliminium ligand show antiproliferative activity towards A2780 and A2780cisR cancer cell lines, and possess several ideal features for a drug, namely multi‐gram scale synthesis, wide structural diversity, amphiphilicity, good stability in aqueous media and selectivity against cancerous cells compared to HEK‐293 normal cells. The Cover graphic has been designed by Claudia Mazzantini and Giulia Maltinti. More information can be found in the Full Paper by P. J. Dyson, F. Marchetti, et al. on page 14801.