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Cover Feature: Potent and Selective Cytotoxic and Anti‐inflammatory Gold(III) Compounds Containing Cyclometalated Phosphine Sulfide Ligands (Chem. Eur. J. 62/2019)
Author(s) -
Reddy T. Srinivasa,
Pooja Deep,
Privér Steven H.,
Luwor Rodney B.,
Mirzadeh Nedaossadat,
Ramesan Shwathy,
Ramakrishna Sistla,
Karri Shailaja,
Kuncha Madhusudana,
Bhargava Suresh K.
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201904011
Subject(s) - phosphine , chemistry , sulfide , combinatorial chemistry , gold compounds , ligand (biochemistry) , biochemistry , organic chemistry , receptor , catalysis
Newly designed gold(III) compounds containing cycloaurated phosphine sulfide ligands with dual properties, namely anti‐cancer and anti‐inflammatory activity, offer a safe and effective treatment for cancer. A common drawback of gold(III) complexes is their instability under physiological conditions, which has been overcome by shedding light on the desirable ligand features that stabilize gold compounds, making them suitable for biological investigations. More information can be found in the Full Paper by R. B. Luwor, N. Mirzadeh, S. K. Bhargava et al. on page 14089.