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Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp 3 )−C(sp 2 ) Bond Formation
Author(s) -
González María J.,
Breit Bernhard
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201903708
Subject(s) - iridium , catalysis , intermolecular force , cobalt , stoichiometry , reagent , reductive elimination , chemistry , ene reaction , photochemistry , functional group , molecule , medicinal chemistry , inorganic chemistry , organic chemistry , polymer
A new methodology to form C(sp 3 )−C(sp 2 ) bonds by visible‐light‐driven intermolecular reductive ene–yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional‐group tolerance and atom economy.