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Chiral Benzazaborole‐Catalyzed Regioselective Sulfonylation of Unprotected Carbohydrate Derivatives
Author(s) -
Kuwano Satoru,
Hosaka Yusei,
Arai Takayoshi
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201903443
Subject(s) - regioselectivity , carbohydrate , chemistry , catalysis , organic chemistry , kinetic resolution , carbohydrate chemistry , combinatorial chemistry , enantioselective synthesis
Abstract Chiral benzazaborole‐catalyzed regioselective sulfonylations of unprotected carbohydrate derivatives have been developed. This methodology enables direct regioselective functionalization of the secondary OH group in carbohydrate in the presence of the primary OH group. By using the chiral organoboron catalysis, kinetic resolution of the carbohydrate derivatives was also achieved.