Premium
A Closed Chemobrionic System as a Biochemical Delivery Platform
Author(s) -
Angelis Georgios,
Zayed Dimitris Nabil,
Karioti Anastasia,
Lazari Diamanto,
Kanata Eirini,
Sklaviadis Theodoros,
Pampalakis Georgios
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201903255
Subject(s) - biomolecule , chemistry , dna , membrane , plasmid , nanotechnology , silicate , biophysics , chemical engineering , biochemistry , materials science , biology , engineering , organic chemistry
Inorganic cells bearing calcium silicate membranes were prepared and resembled closed chemical gardens. It was demonstrated that these inorganic cells can successfully be loaded with natural products, proteins and plasmid DNA, and their cargo can be released in a controlled manner. These cells demonstrated the ability of chemical gardens to act as platforms for the sustained delivery of biomolecules and are expected to introduce chemical gardens in the field of biosciences.