Premium
Simulated Sunlight Selectively Modifies Maillard Reaction Products in a Wide Array of Chemical Reactions
Author(s) -
Hemmler Daniel,
Gonsior Michael,
Powers Leanne C.,
Marshall James W.,
Rychlik Michael,
Taylor Andrew J.,
SchmittKopplin Philippe
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201902804
Subject(s) - maillard reaction , chemistry , amino acid , photodegradation , photochemistry , ribose , glycation , mass spectrometry , organic chemistry , photocatalysis , biochemistry , enzyme , chromatography , catalysis , receptor
The photochemical transformation of Maillard reaction products (MRPs) under simulated sunlight into mostly unexplored photoproducts is reported herein. Non‐enzymatic glycation of amino acids leads to a heterogeneous class of intermediates with extreme chemical diversity, which is of particular relevance in processed and stored food products as well as in diabetic and age‐related protein damage. Here, three amino acids (lysine, arginine, and histidine) were reacted with ribose at 100 °C in water for ten hours. Exposing these model systems to simulated sunlight led to a fast decay of MRPs. The photodegradation of MRPs and the formation of new compounds have been studied by fluorescence spectroscopy and nontargeted (ultra)high‐resolution mass spectrometry. Photoreactions showed strong selectivity towards the degradation of electron‐rich aromatic heterocycles, such as pyrroles and pyrimidines. The data show that oxidative cleavage mechanisms dominate the formation of photoproducts. The photochemical transformations differed fundamentally from “traditional” thermal Maillard reactions and indicated a high amino acid specificity.