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Mild and Practical Dirhodium(II)/NHPI‐Mediated Allylic and Benzylic Oxidations with Air as the Oxidant
Author(s) -
Wang Yi,
Chen Xiaochuan,
Jin Hong,
Wang Yuanhua
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201902739
Subject(s) - allylic rearrangement , dissociation (chemistry) , chemistry , catalysis , axial symmetry , medicinal chemistry , bond dissociation energy , open air , photochemistry , organic chemistry , physics , engineering , architectural engineering , quantum mechanics
Aerobic allylic and benzylic oxidations catalyzed by dirhodium(II) complexes with N ‐hydroxyphthalimide (NHPI) are described. The open flask reaction occurs at mild temperature, using air as the oxidant. Mechanistic studies suggest that dirhodium(II) complexes axially coordinate with NHPI to activate the O−H bond in NHPI and decrease the bond‐dissociation energy (BDE).