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Cover Feature: Exploring the Role of Coinage Metalates in Trifluoromethylation: A Combined Experimental and Theoretical Study (Chem. Eur. J. 40/2019)
Author(s) -
Martínez de Salinas Sara,
Mudarra Ángel L.,
Odena Carlota,
Martínez Belmonte Marta,
BenetBuchholz Jordi,
Maseras Feliu,
PérezTemprano Mónica H.
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201902672
Subject(s) - trifluoromethylation , cover (algebra) , reactivity (psychology) , halide , feature (linguistics) , aryl , chemistry , combinatorial chemistry , computer science , organic chemistry , philosophy , engineering , mechanical engineering , linguistics , alkyl , trifluoromethyl , medicine , alternative medicine , pathology
For the first time, the door to access selectively Cu(CF 3 ) 2 − have been unlocked. These species, ubiquitous in trifluoromethylation reactions, displayed a superior reactivity towards aryl halides than its argentate and aurate congeners. Merging experimental and computational approaches, a complex mechanistic scenario is unraveled, through a CuI/III process, with the participation of more reactive species such as (DMF)CuCF 3 , generated through multiple equilibria. More information can be found in the Communication by F. Maseras, M. H. Pérez‐Temprano et al. on page 9390.